Pornpun Vivithanaporn

พรพรรณ วิวิธนาภรณ์

Special Instructor
Associate Professor
  • B.Sc. (Pharmaceutical Sciences, magna cum laude) Chulalongkorn University, Thailand
  • Ph.D. (Pharmacology) University of Texas Medical Branch, USA
Current Research
  • Glia cells: inflammation and cancers
  • Ospondpant D, Phuagkhaopong S, Suknuntha K, Sangpairoj K, Kasemsuk T, Srimaroeng C, Vivithanaporn P. Cadmium induces apoptotic program imbalance and cell cycle inhibitor expression in cultured human astrocytes. Environ Toxicol Pharmacol. 2019 Jan;65:53-59.
  • Suknuntha K, Yubolphan R, Krueaprasertkul K, Srihirun S, Sibmooh N, Vivithanaporn P*. Leukotriene receptor antagonists inhibit mitogenic activity in triple negative breast cancer cells. Asian Pac J Cancer Prev. 2018 Mar 27;19(3):833-7.
  • Kasemsuk T, Vivithanaporn P, Unchern S*. Anti-inflammatory effects of bromelain in lps-induced human U937 macrophages. Chiang Mai J Sci 2018;45(1):299-307.
  • Piromkraipak P, Sangpairoj K, Tirakotai W, Chaithirayanon K, Unchern S, Supavilai P, Power C, Vivithanaporn P*. Cysteinyl leukotriene receptor antagonists inhibit migration, invasion, and expression of MMP-2/9 in human glioblastoma. Cell Mol Neurobiol 2018 Mar;38(2):559-73.
  • Parakaw T, Suknuntha K, Vivithanaporn P, Schlagenhauf A, Topanurak S, Fucharoen S, Pattanapanyasat K, Schechter A, Sibmooh N, Srihirun S*. Platelet inhibition and increased phosphorylated vasodilator-stimulated phosphoprotein following sodium nitrite inhalation. Nitric Oxide 2017 Jun 1;66:10-16.
  • Phuagkhaopong S, Ospondpant D, Kasemsuk T, Sibmooh N, Soodvilai S, Power C, Vivithanaporn P*. Cadmium-induced IL-6 and IL-8 expression and release from astrocytes are mediated by MAPK and NF-κB pathways. Neuro Toxicology 2017;60:82-91.
  • Sangpairoj K, Chaithirayanon K, Vivithanaporn P, Siangcham T, Jattujan P, Poomtong T, Nobsathian S, Sobhon P*. Extract of the sea cucumber, Holothuria scabra, induces apoptosis in human glioblastoma cell lines. Funct Foods Health Dis 2016;6(7):452-68.
  • Nontarach A, Srihirun S, Chaturapanich G, Unchern S, Swaddiwudhipong W, Pattanapanyasat K, Chamchoi A, Vivithanaporn P, Visoottiviseth P, Sibmooh N. Increased platelet activation in subjects chronically exposed to cadmium: A pilot study. Platelets. 2016;27(2):136-42.
  • Vivithanaporn P, Asahchop EL, Acharjee S, Baker GB, Power C*. HIV protease inhibitors disrupt astrocytic glutamate transporter function and neurobehavioral performance. AIDS 2016;30(4):543-52.
  • Acharjee S, Branton WG, Vivithanaporn P, Maingat F, Paul AM, Dickie P, et al. HIV-1 Nef expression in microglia disrupts dopaminergic and immune functions with associated mania-like behaviors. Brain Behav Immun. 2014;40:74-84.
  • Polyak MJ, Vivithanaporn P, Maingat FG, Walsh JG, Branton W, Cohen EA, et al. Differential type 1 interferon-regulated gene expression in the brain during AIDS: interactions with viral diversity and neurovirulence. FASEB J. 2013;27(7):2829-44.
  • Ontawong A, Saowakon N, Vivithanaporn P, Pongchaidecha A, Lailerd N, Amornlerdpison D, et al. Antioxidant and renoprotective effects of Spirogyra neglecta (Hassall) Kutzing extract in experimental type 2 diabetic rats. Biomed Res Int. 2013;2013:820786.
  • McCombe JA, Vivithanaporn P, Gill MJ, Power C. Predictors of symptomatic HIV-associated neurocognitive disorders in universal health care. HIV Med. 2013;14(2):99-107.
  • Maingat FG, Polyak MJ, Paul AM, Vivithanaporn P, Noorbakhsh F, Ahboucha S, et al. Neurosteroid-mediated regulation of brain innate immunity in HIV/AIDS: DHEA-S suppresses neurovirulence. FASEB J. 2013;27(2):725-37.
  • Vivithanaporn P, Nelles K, Deblock L, Newman SC, Gill MJ, Power C. Hepatitis C virus co-infection increases neurocognitive impairment severity and risk of death in treated HIV/AIDS. J Neurol Sci. 2012;312(1-2):45-51.
  • Power C, Hui E, Vivithanaporn P, Acharjee S, Polyak M. Delineating HIV-Associated Neurocognitive Disorders Using Transgenic Models: The Neuropathogenic Actions of Vpr. J Neuroimmune Pharmacol. 2012;7(2):319-31.
  • Vivithanaporn P, Gill MJ, Power C. Impact of current antiretroviral therapies on neuroAIDS. Expert Rev Anti Infect Ther. 2011;9(4):371-4.
  • Na H, Acharjee S, Jones G, Vivithanaporn P, Noorbakhsh F, McFarlane N, et al. Interactions between human immunodeficiency virus (HIV)-1 Vpr expression and innate immunity influence neurovirulence. Retrovirology. 2011;8:44.
  • Vivithanaporn P, Maingat F, Lin LT, Na H, Richardson CD, Agrawal B, Cohen EA, Jhamandas JH, Power C*. Hepatitis C virus core protein induces neuroimmune activation and potentiates Human Immunodeficiency Virus-1 neurotoxicity. PLoS One. 2010;5(9): e12856.
  • Vivithanaporn P, Heo G, Gamble J, Krentz HB, Hoke A, Gill MJ, Power C. Neurologic disease burden in treated HIV/AIDS predicts survival. A population-based study. Neurology 2010;75(13):1150-8.
  • Lee K, Vivithanaporn P, Siemieniuk R, Krentz HB, Maingat F, Gill MJ, Power C. Clinical outcomes and immune benefits of anti-epileptic drug therapy in HIV/AIDS. BMC Neurol2010;10(1):44.
  • Maingat F, Viappiani S, Zhu Y, Vivithanaporn P, Ellestad KK, Holden J, Silva C, Power C. Regulation of lentivirus neurovirulence by lipopolysaccharide conditioning: suppression of CXCL10 in the brain by IL-10. J Immunol. 2010;184(3):1566-74.
  • Gill MB, Vivithanaporn P, Swanson GT. Glutamate binding and conformational flexibility of ligand-binding domains are critical early determinants of efficient kainate receptor biogenesis. J Biol Chem. 2009;284(21):14503-12.
  • Maingat F, Vivithanaporn P, Zhu Y, Taylor A, Baker G, Pearson K, et al. Neurobehavioral performance in feline immunodeficiency virus infection: integrated analysis of viral burden, neuroinflammation, and neuronal injury in cortex. J Neurosci. 2009;29(26):8429-37.
  • Vivithanaporn P, Lash LL, Marszalec W, Swanson GT. Critical roles for the M3-S2 transduction linker domain in kainate receptor assembly and postassembly trafficking. J Neurosci. 2007;27(39):10423-33.
  • Vivithanaporn P, Yan S, Swanson GT. Intracellular trafficking of KA2 kainate receptors mediated by interactions with coatomer protein complex I (COPI) and 14-3-3 chaperone systems. J Biol Chem. 2006;281(22):15475-84.