Theses

2023: 
TitleStudentAdvisor
EFFECTS OF CENTELLA ASIATICA EXTRACT (ECa233) ON IRON METABOLISM IN ฺBETA-THALASSEMIC MICEMISS PUNTITA ANUTAGERNGKUN
(M.Sc.)
NOPPAWAN PHUMALA MORALES

ANTICANCER EFFECT OF PINOSTROBIN ON MCF-7 AND MDA-MB-231 HUMAN BREAST CANCER CELL LINES THROUGH REGULATION OF EPITHELIAL MESENCHYMAL TRANSITIONMISS PIMRAPAT JONGJANG
(M.Sc.)



DARAWAN PINTHONG




2022: 
TitleStudentAdvisor
FUNCTIONAL CHARACTERIZATION OF RECOMBINANT FACTOR IX FROM F9 GENE TRANSFECTED IN IMMORTALIZED HEPATOCYTE-LIKE CELL LINEMISS KULTASNIM KADO
(M.Sc.)



PANSAKORN TANRATANA




THE PATHOGENIC MECHANISM UNDERLYING SELECTIVE DISRUPTION OF TISSUE FACTOR PATHWAY INHIBITOR-BINDING EXOSITES ON FACTOR VIIMISS KARNSASIN SEANOON
(Ph.D.)


PANSAKORN TANRATANA



EFFICACY EVALUATION OF LOSARTAN TREATMENT ON INFRAPATELLAR FAT PAD/SYNOVIAL FIBROSIS AND MUSCLE ATROPHY IN AN OSTEOARTHRITIS RAT MODELMISS ORADA SRIWATANANUKULKIT
(Ph.D.)


RUEDEE HEMSTAPAT




2021:
TitleStudentAdvisor
THE EFFECT OF ANDROGRAPHOLIDE ON THE ESTROGEN RECEPTOR SIGNALING PATHWAY IN BREAST CANCER CELL LINESMISS RUHAINEE TOHKAYOMATEE
(Ph.D.)

DARAWAN PINTHONG



2020:       
Title Student Advisor  
APOPTOTIC, ANTIPROLIFERATIVE AND INFLAMMATORY EFFECTS OF NICKEL ON HUMAN ASTROCYTES MISS RUEDEEMARS YUBOLPHAN (Ph.D.) PORNPUN VIVITHANAPORN  
       
EFFECT OF MORINGA OLEIFERA LEAF EXTRACT ON NITRIC OXIDE PRODUCTION BY ENDOTHELIAL CELLS MR. PEERAKARN WISITWONG (M.Sc.) NATHAWUT SIBMOOH  
       
PLASMA KYNURENINE/TRYPTOPHAN RATIOS AS PREDICTIVE BIOMARKERS FOR STAGE III NON-SMALL CELL LUNG CANCER PATIENTS RECEIVING DURVALUMAB MISS ONANONG KONGJORNRAK (M.Sc.) PIMTIP SANVARINDA  
       
MECHANISM UNDERLYING APOPTOTIC EFFECTS OF HALYMENIA DURVILLEI EXTRACTS ON TRIPLE-NEGATIVE BREAST CANCER CELLS: OXIDATIVE STRESS, INTRINSIC APOPTOTIC PATHWAY, DNA DAMAGE, AND ENDOPLASMIC RETICULUM STRESS MISS RAPEEWAN SETTACOMKUL (M.Sc.) PORNPUN VIVITHANAPORN  
   
2019:      
 Title Student  Advisor  
STUDY OF LIPID RADICALS DERIVED FROM LDL AND HDL OXIDATION IN BETA-THALASSEMIA MR. PAKAWIT LERKSAIPHENG (M.Sc.) NOPPAWAN PHUMALA MORALE  
       
CHONDROPROTECTIVE MECHANISM OF BIOACTIVE COMPOUNDS IN MORUS ALBA L. IN HUMAN CHONDROCYTE CELL LINE MISS CHAYANEE LAOWITTAWAT (M.Sc.) RUEDEE HEMSTAPAT  
       
IN VITRO ANTIOXIDANT AND ANTI-INFLAMMATORY ACTIVITY OF THE ACTIVE COMPOUNDS FROM FINGERROOT EXTRACT MR. CHANATHIP DUANGTHA (M.Sc.) RUEDEE HEMSTAPAT  
       
NITRITE AND NITRATE LEVELS IN BREAST CANCER TISSUES FROM PATIENTS MR. PEERAWICH KONGKAEW (M.Sc.) NATHAWUT SIBMOOH  

 
2018:      
 Title Student  Advisor  
 IMPROVEMENT OF ENDOTHELIAL FUNCTION IN HEMOGLOBIN E/ -THALASSEMIA BY DEFERIPRONE MISS THANAPORN SRIWANTANA (Ph.D.) NATHAWUT SIBMOOH  
       
THE EFFECT OF PLUMBAGIN ON HIF-1 ALPHA EXPRESSION UNDER HYPOXIC CONDITION IN BREAST CANCER MCF-7 CELLS MISS SUPAWAN JAMPASRI (M.Sc.) DARAWAN PINTHONG  
       
EFFECTS OF WNT INHIBITION ON DIFFERENTIATION, PROLIFERATION AND APOPTOSIS OF HUMAN MYELOID LEUKEMIA CELL LINES  MISS THANYATIP THITA (M.Sc.) PORNTIPA KORPRASERTTHAWORN  
       
 INCREASED ENDOTHELIAL NITRIC OXIDE SYNTHASE AND GUANYLATE CYCLASE EXPRESSION IN ESTROGEN RECEPTOR POSITIVE BREAST CANCER TISSUE FROM PATIENTS  MISS QIAN CHEN (M.Sc.) NATHAWUT SIBMOOH  
       
 EXPRESSION LEVELS OF 5-LIPOXYGENASE AND LEUKOTRIENE RECEPTORS IN MENINGIOMAS AND GLIOMAS  MISS RUENRUTHAI KAEOPU (M.Sc.) PORNPUN VIVITHANAPORN  
       
 EFFECTS OF CYSTEINYL LEUKOTRIENE RECEPTOR ANTAGONISTS ON APOPTOTIC-RELATED PROTEIN, CELL CYCLE REGULATOR PROTEIN, AND MATRIX METALLOPROTEINASE EXPRESSION IN TRIPLE-NEGATIVE BREAST CANCER CELLS  MISS KANOKPAN KRUEAPRASERTKUL (M.Sc.) PORNPUN VIVITHANAPORN  

 
2017 :      
Title Student Advisor  
EFFECT OF IRON CHELATOR ON IRON DISTRIBUTION AND IRON DEPOSITION IN THE BONE OF -THALASSEMIA MICE MISS SCARLETT SHANIKA DESCLAUX  (M.Sc.) WARINKARN HEMSTAPAT  
       
CEFAZOLIN IMPREGNATED OXIDIZED REGENERATED CELLULOSE/ POLYCAPROLACTONE COMPOSITE FOR USING AS ANTIBACTERIAL SYNTHETIC DURAL SUBSTITUTE MISS ARUNNEE SANPAKITWATTANA  (M.Sc.) WARINKARN HEMSTAPAT  
       
IN VITRO STUDY OF POMELO EXTRACTS ON PLATELET FUNCTIONS MISS JINDAPORN JANPRASIT  (M.Sc.) NOPPAWAN PHUMALA MORALES  
       
THE CYTOTOXIC AND ANTI-MIGRATION EFFECTS OF CYSTEINYL LEUKOTRIENE RECEPTOR-1 ANTAGONISTS IN MDA-MB-231 HUMAN BREAST CANCER CELLS MISS DIANA  (M.Sc.) PORNPUN VIVITHANAPORN  
       
GANODERIC ACIDS: G-QUADRUPLEX LIGANDS WITH ANTICANCER EFFECT MR. SITTICHAI SILLAPAPONGWARAKORN (Ph.D.) PORNTIP SUPAVILAI  
       
PHARMACOGENOMICS AND PHARMACOKINETICS OF TENOFOVIR IN HIV-1 INFECTED PATIENTS MR. NARIT WIRIYAKOSOL (Ph.D.) DARAWAN PINTHONG  

 
2016 :      
Title Student Advisor  
PHARMACOGENOMICS OF DRUG METABOLIZING ENZYMES AND TRANSPORTERS IN RISPERIDONE TREATED AUTISM SPECTRUM DISORDER THAI CHILDREN AND ADOLESCENTS MR. SADEEP MEDHASI (PhD) DARAWAN PINTHONG  
       
EFFECTS OF LEUKOTRIENE RECEPTOR ANTAGONISTS AGAINST HUMAN GLIOMA CELLS MRS. PANNAREE PIROMKRAIPAK (PhD) PORNPUN VIVITHANAPORN  
       
 THE EFFECTS OF PINEAPPLE, WATERMELON, GUAVA, AND YAM BEAN ON BLOOD PRESSURE AND PLATELET FUNCTION IN HEALTHY VOLUNTEERS.  MISS THITIPORN THAPTIMTHONG (PhD)  SUPEENUN UNCHERN  
       
THE EFFECT OF BROMELAIN ON LIPID PEROXIDATION AND PGE2 PRODUCTION IN PATIENTS WITH PRIMARY KNEE OSTEOARTHRITIS MISS THITIMA KASEMSUK (PhD) SUPEENUN UNCHERN  
       
ASSOCIATION BETWEEN BUTYRYLCHOLINESTERASE K VARIANT AND INTERLEUKIN-18 GENES IN MILD COGNITIVE IMPAIRMENT MISS NATSALIL PONGTHANARACHT (PhD) PORNTIP SUPAVILAI  
       
INCREASED PLATELET-DERIVED GROWTH FACTOR-BB IN B-THALASSEMIA/HEMOGLOBIN E PATIENTS AND ITS EFFECT ON PROLIFERATION OF HUMAN PULMONARY ARTERY ENDOTHELIAL CELLS Dental Surgeon KRIT RATTANAWONSAKUL (M.Sc.) NATHAWUT SIBMOOH  
       
EFFECT OF INHALED NEBULIZED NITRITE ON PLATELET ACTIVITY IN HEALTHY VOLUNTEERS TIPPARAT PARAKAW (M.Sc.)  NATHAWUT SIBMOOH  
       
ACUTE CADMIUM EXPOSURE INDUCES INTERLEUKIN-6 EXPRESSION AND SECRETION THROUGH ERK1/2 AND NF-KB PATHWAYS IN HUMAN ASTROCYTES MISS SUTTINEE PHUAGKHAOPONG (M.Sc.) PORNPUN VIVITHANAPORN  
       
NEW APPROACH FOR USING SCAFFOLD FREE CARTILAGE CONSTRUCT OBTAINED FROM ADIPOSE-DERIVED MESENCHYMAL STEM CELLS (ASCS) FOR ARTICULAR CARTILAGE REGENERATION MISS ORADA SRIWATANANUKULKIT (M.Sc.) WARINKARN HEMSTAPAT  
       
INHALED NEBULIZED SODIUM NITRITE HAS NO EFFECT ON OXIDATIVE STRESS IN HEALTHY AND HEMOGLOBIN E/B-THALASSEMIC SUBJECTS MISS JIRADA KAEWCHUCHUEN (M.Sc.) SUPEENUN UNCHERN  

 
2015 :      
Oxidized regenerated cellulose/polycaprolactone composite for use as a synthetic dura mater Thunyanun Theeranattapong (M.Sc.) Warinkarn Hemstapat  
       
Regulatory role of ERK1/2 on autophage-mediated neuroprotective effect of quercetin Sasima Chotithammakul (M.Sc.) Pimtip Sanvarinda  
       
Mass spectrometric profiling of salivary gland protein of arbovirus vector Natthinee Jiraphan (M.Sc.) Noppawan Phumala Morales  
       
Development of microcarrier cell culture for characterization of free radical reaction in microglia cells Pattama Yamsiri (M.Sc.) Noppawan Phumala Morales  
       
Study of oxidized regenerated cellulose/ polycaprolactone composite in a rabbit model Ticomporn Luangwattanawilai (M.Sc.) Warinkarn Hemstapat  

 
2014 :      
Effects of iron chelators on oxidative stress and different tissues damage in iron overloaded-thalassemic mice Paranee Yatmark (Ph.D.) Noppawan  Phumala  Morales  
       
The effects of cadmium and inorganic mercury on astrocytes Dusadee Ospondpant (M.Sc.) Pornpun Vivithanaporn  
       
The study of flavivirus induced reactive oxygen species (ROS) in microglia cells Lattapon Suwanprinya (M.Sc.) Noppawan  Phumala  Morales  
       
Effects of miroestrol on breast cancer cell line proliferation through estrogen receptor-dependent and independent pathway Sirin Khantichaikajon (M.Sc.) Darawan  Pinthong  
       
Estrogen modulators exert their antiproliferative effect on MCF-7 cell line through PI3K signaling pathway Chawanee Kerdsomboon (M.Sc.) Darawan  Pinthong  
       
Characterization of NFAT expression in human glioma and its correlation with tumor grade Teerapon Pacharoen (M.Sc.) Nattinee Jantaratnotai  
       
Molecular dynamics simulation study of human butyrylcholinesterase with its nihibitors Pamorn Chittavanich (M.Sc.) Porntip Supavilai  
       
Study the binding of anti-alzheimer’s drugs to human acetylcholinesterase based on molecular dynamics simulation Bodee Nutho (M.Sc.) Porntip Supavilai  

 
2013 :      
Pharmacogenetics of prognostic factors in Thai hormonal positive breast cancer patients receiving adjuvant tamoxifen Insee Sensorn (Ph.D.) Darawan Pinthong  
       
Autophagy-mediated clearance of alpha-synuclein underlies the neuroprotective effect of quercetin and its derivative, 3-methyl quercetin, in H2O2-treated SH-SY5Y neuroblastoma cell line Thanapong Kanyapreedakul (M.Sc.) Pimtip Sanvarinda  
       
Effect of iron chelators on hepcidin synthesis in wild-type and thalassemic mice with iron overload Surasak Wichaiyo (M.Sc.) Noppawan  Phumala  Morales  
       
Antioxidant activities of White Mulberry stem extract on osteoarthritis progression in a rat model of osteoarthritis Pham Phuong Phi (M.Sc.) Warinkarn Hemstapat  
       
Cytoprotective effects of pure compounds from Curcuma Comosa on hydrogen peroxide-induced SH-SY5Y cell death Zon Mie Khin Aung (M.Sc.) Yupin  Sanvarinda  
       
Effect of oxyresveratrol from Artocarpus lakoocha Roxb. on neutrophil functions Krittanai Maneenual (M.Sc.) Payong Wanikiat  
       
Dualistic role of caffeine, as main additive of Yaba, on methamphetamine-induced neurotoxicity Rujiraporn Pitaksalee (M.Sc.) Yupin  Sanvarinda  

 
2012 :      
Influence of amino acid substitutions on the catalytic activity and substrate selectivity of UGT1A9 Porntipa Korprasertthaworn (Ph.D.) Krongtong Yoovathaworn  
       
Identification of metabolites of flavonoids from Thai fruits in human Lalita Chomphen (M.Sc.) Noppawan  Phumala  Morales  
       
Effect of iron chelators on intracellular ROS production in iron overloaded microglia cells Samaphorn Maneethep (M.Sc.) Noppawan  Phumala  Morales  
       
Increased nitric oxide degradation by plasma of β-thalassemia/hemoglobin E subjects Amara Wankham (M.Sc.) Nathawut Sibmooh  
       
Investigation of the effects of bromelain in anterior cruciate ligament transection (ACLT)-induced osteoarthritis in rats Sujinna Lekmeechai (M.Sc.) Warinkarn Hemstapat  
       
Inhibitory effects of a pure compound isolated from Curcuma Comosa in lipopolysaccharide-induced microglial activation Nittaya Jiamvoraphong (M.Sc.) Yupin  Sanvarinda  
       
Structure-activity relationship of quercetin and its analogs on their antioxidant properties and neuroprotective effect Panthipa Supraditaporn (M.Sc.) Yupin  Sanvarinda  
       
Cytoprotective effects of pure compounds from Curcuma comosa on hydrogen peroxide-induced C6 astroglial cell death Jaturavit Vattanarongkup (M.Sc.) Nattinee Jantaratnotai  

 
2011 :      
The effects of nitrite on platelet function Sirada Srihirun (Ph.D.) Nathawut Sibmooh  
       
Roles of caffeine in Ya-Ba on the effects of methamphetamine-induced acute neurotoxicity in the rat brain Pol.Lt.Col. Theerin Sinchai (Ph.D.) Surin Plasen  
       
Nitric oxide bioavailability in thalassemia Thitiwat Suvachananonda (M.Sc.) Nathawut Sibmooh  
       
Nitrite levels in β-thalassemia/hemoglobin E patients Thanaporn Sriwantana (M.Sc.) Nathawut Sibmooh  
       
Antioxidant and anti-mutagenic effects of Thai white mulberry (Morus alba L.) and butterfly pea (Clitoria ternatea L.) teas Siriyaporn Dhammachat (M.Sc.) Auratai Aramphongphan  
       
Binding studies of estrogenic compounds to recombinant estrogen receptors compared to classical estrogen receptors Naruemon Sangob (M.Sc.) Darawan  Pinthong  
       
Development of surface plasmon resonance biosensor to study estrogenic compound binding to estrogen receptors Purada Chokprajakchad (M.Sc.) Darawan  Pinthong  
       

 
2010 :      
Characterization of estrogen receptor in vascular and leukocyte function Nipapan Malisorn (Ph.D.) Payong Wanikiat  
       
The neuroprotective effects of Curcumin I and its analogues on 6-hydroxydopamine (6-OHDA)-induced neurotoxicity in SH-5Y5Y cells Yamaratee Jaisin (Ph.D.) Yupin Sanvarinda  
       
Evaluation of pharmacological-toxicological effects of Thai ganoderma lucidum Theera Dalodom (M.Sc.) Auratai Aramphongphan  
       
Effects of hemin on antimalarial activity of artemisinin and quinoline antimalarial drugs against cultured Plasmodium falciparum Sunanta Tangnitipong (M.Sc.) Nathawut  Sibmooh  
       
Antioxidative systems protect against hemoglonbin-induced oxidative damage in Aedes aegypti Lalinthip Saeaue (M.Sc.) Noppawan  Phumala Morales  
       
The effects of Moringa oleifera Lam leaf extracts on lipopolysaccharide-induced microglial activation Busarat Karachot (M.Sc.) Yupin Sanvarinda  
       
An EPR spin trapping study of iron overload-induced free radical production in microglia cells Guntarika Suntivich (M.Sc.) Noppawan  Phumala Morales  

 
2009 :  
Measurement of putative regulatory and signaling molecules following rhodopsin receptor stimulation in a unicellular eukaryotic model, Chlamydomonas reinhardtii Maskiet Boonyareth (Ph.D.) Darawan Pinthong  
       
Anti-inflammatory effect of a novel compound from Curcuma comosa in lipopolysaccharide-induced microglial activation Anusorn Thampithak (Ph.D.) Yupin Sanvarinda  
       
Effect of pure compounds from Polyalthia glaca andPhyllanthus albidiscus on human neutrophil functional responsiveness and T-lymphocyte proliferation Surapong Lauhapiyakun (M.Sc.) Payong Wanikiat  
       
The neuroprotective effects of purified compound extracted from curcuma longa against 6-OHDA-induced dopaminergic neurotoxicity in SH-SY5Y cells Benjawan Meesarapee (M.Sc.) Yupin Sanvarinda  
       
Effect of derris scandens extract on oxidative stress status and status and platelet function of knee osteoarthritis patients compared with naproxen Pathomwat Wongrattanakamon (M.Sc.) Supeenun Unchern  

 
2008 :  
Neuroprotective effects of Ganoderma Lucidum mycelium extracts in neuroblastoma SH-SY5Y cells Sirinthorn Pinweha (Ph.D.) Porntip Supavilai  
       
Effect of atorvastatin on toll-like receptor 4 clustering into lipid raft Praveen Chansrichavala (Ph.D.) Udom Chantharaksri  
       
The mechanisms of tetrahydrobiopterin-induced dopaminergic cell death Vasutakarn Chongthammakun (Ph.D.) Yupin Sanvarinda  
       
Neuroprotective effect of curcumin on chemical-induced oxidative stress in SH-Sy5Y neuroblastoma cells Jantra Chalasin (M.Sc.) Porntip Supavilai  
       
Genotyping study of UGT1A9 in Thai population Porntipa Korprasertthaworn (M.Sc.) Krongtong  Yoovathaworn  
       
Comparative pharmacokinetic study of two single doses of deferiprone in β-halassemia/hemoglobin E patients Supot Rodrat (M.Sc.) Noppawan  Phumala  Morales  
       
ESR spin labeling studies on the site of iron-induced free radical reaction in low density lipoprotein Pacharaporn Chunephisal (M.Sc.) Noppawan  Phumala Morales  
       
The study of antiplatelet activity of deferiprone Pannaree Chaivichit (M.Sc.) Noppawan  Phumala Morales  
       

 
2007 :  
Effects of coding region mutations on UGT1A1 enzyme activity and genetic polymorphisms of UGT1A1 in a Thai population Wandee Udomuksorn (Ph.D.) Krongtong  Yoovathaworn  
       
       
A pharmacokinetic study of deferiprone and its metabolite in β-thalassemia/Hb E with different UGT1A genotypes Lie Michael George Limenta (Ph.D.) Noppawan  Phumala Morales  
       
       
Effect of ethanol on alpha4/6 beta3 delta GABAa receptors Panida Chutsrinopkun (Ph.D.) Porntip Supavilai  
       
The effect of Butea superba Roxb. Thai traditional medicine, on endogenous steroid levels in human Sutheema Nimsoongnern (M.Sc.) Darawan Pinthong