Publications

• Yatmark P, Morales NP, Chaisri U, Wichaiyo S, Hemstapat W, Srichairatanakool S, et al. Iron distribution and histopathological characterization of the liver and heart of β-thalassemic mice with parenteral iron overload: Effects of deferoxamine and deferiprone. Exp Toxicol Pathol. 2014;66(7):333-43.
• Grumbles RM, Almeida VW, Casella GT, Wood PM, Hemstapat K, Thomas CK. Motoneuron replacement for reinnervation of skeletal muscle in adult rats. J Neuropathol Exp Neurol. 2012;71(10):921-30.
• Alagille D, DaCosta H, Chen Y, Hemstapat K, Rodriguez A, Baldwin RM, et al. Potent mGluR5 antagonists: pyridyl and thiazolyl-ethynyl-3,5-disubstituted-phenyl series. Bioorg Med Chem Lett. 2011;21(11):3243-7.
• Hemstapat K, Le L, Edwards SR, Smith MT. Comparative studies of the neuro-excitatory behavioural effects of morphine-3-glucuronide and dynorphin A(2-17) following spinal and supraspinal routes of administration. Pharmacol Biochem Behav. 2009;93(4):498-505.
• Hemstapat K, Da Costa H, Nong Y, Brady AE, Luo Q, Niswender CM, et al. A novel family of potent negative allosteric modulators of group II metabotropic glutamate receptors. J Pharmacol Exp Ther. 2007;322(1):254-64.
• Chen Y, Nong Y, Goudet C, Hemstapat K, de Paulis T, Pin JP, et al. Interaction of novel positive allosteric modulators of metabotropic glutamate receptor 5 with the negative allosteric antagonist site is required for potentiation of receptor responses. Mol Pharmacol. 2007;71(5):1389-98.
• Hemstapat K, de Paulis T, Chen Y, Brady AE, Grover VK, Alagille D, et al. A novel class of positive allosteric modulators of metabotropic glutamate receptor subtype 1 interact with a site distinct from that of negative allosteric modulators. Mol Pharmacol. 2006;70(2):616-26.
• Galici R, Jones CK, Hemstapat K, Nong Y, Echemendia NG, Williams LC, et al. Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice. J Pharmacol Exp Ther. 2006;318(1):173-85.
• de Paulis T, Hemstapat K, Chen Y, Zhang Y, Saleh S, Alagille D, et al. Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes. J Med Chem. 2006;49(11):3332-44.
• Hemstapat K, Smith MT, Monteith GR. Measurement of intracellular Ca2+ in cultured rat embryonic hippocampal neurons using a fluorescence microplate reader: potential application to biomolecular screening. J Pharmacol Toxicol Methods. 2004;49(2):81-7.
• Hemstapat K, Smith SA, Monteith GR, Smith MT. The neuroexcitatory morphine metabolite, morphine-3-glucuronide (M3G), is not neurotoxic in primary cultures of either hippocampal or cerebellar granule neurones. Pharmacol Toxicol. 2003;93(4):197-200.
• Hemstapat K, Monteith GR, Smith D, Smith MT. Morphine-3-glucuronide's neuro-excitatory effects are mediated via indirect activation of N-methyl-D-aspartic acid receptors: mechanistic studies in embryonic cultured hippocampal neurones. Anesth Analg. 2003;97(2):494-505.